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. 1975 Apr;142(4):533-8.
doi: 10.1002/aja.1001420411.

Cyclic AMP induces ultrastructural differentiation of normal adult human adrenocortical cells cultured in vitro

Cyclic AMP induces ultrastructural differentiation of normal adult human adrenocortical cells cultured in vitro

U Armato et al. Am J Anat. 1975 Apr.

Abstract

Electron microscopic studies have revealed that cyclic AMP, like ACTH, induces structural differentiation of adult human adreno-cortical cells cultured in vitro. These findings support the hypothesis that cyclic AMP can function as an intracellular mediator of the action of ACTH on the human adrenal gland.

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