Polycomb, pairing and PIWI--RNA silencing and nuclear interactions
- PMID: 16876419
- DOI: 10.1016/j.tibs.2006.07.002
Polycomb, pairing and PIWI--RNA silencing and nuclear interactions
Abstract
In Drosophila, the RNA interference (RNAi) genes participate in Polycomb (Pc)-mediated transgene silencing. Recently, the involvement of the RNAi genes in Pc silencing, pairing-sensitive silencing and long-range contacts among Pc-associated sequences has been explored. These Pc-associated sequences are involved with the control of the proper expression of developmental HOX genes.
Comment on
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RNAi components are required for nuclear clustering of Polycomb group response elements.Cell. 2006 Mar 10;124(5):957-71. doi: 10.1016/j.cell.2006.01.036. Cell. 2006. PMID: 16530043
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