Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Dec 24;568(1-2):307-10.
doi: 10.1016/0006-8993(91)91415-w.

Population spike facilitation in the dentate gyrus following glutamate to the lateral supramammillary nucleus

G P Carre  1 , C W Harley
Affiliations

Population spike facilitation in the dentate gyrus following glutamate to the lateral supramammillary nucleus

G P Carre et al. Brain Res. .

Abstract

Glutamate stimulation of the lateral supramammillary nucleus (SUL) in urethane anaesthetized rats produced a substantial increase in the amplitude of the perforant path-evoked population spike in the dentate gyrus, without affecting the population EPSP slope. One third of the spike enhancements lasted longer than 20 min. These data suggest that SUL afferents provide a mechanism for both short- and long-lasting heterosynaptic modulation of hippocampal throughput.

PubMed Disclaimer

Publication types

LinkOut - more resources