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Review
. 2006 Aug;6(4):323-7.
doi: 10.1007/s11892-006-0068-x.

The effect of whole organ pancreas transplantation and PIT on diabetic complications

Timothy C Lee  1 , Neal R Barshes, Erin E Agee, Christine A O'Mahoney, F Charles Brunicardi, John A Goss
Affiliations
Review

The effect of whole organ pancreas transplantation and PIT on diabetic complications

Timothy C Lee et al. Curr Diab Rep. 2006 Aug.

Abstract

Diabetes mellitus is a leading cause of morbidity and mortality in the Western world. Currently, the only forms of beta-cell replacement are whole organ pancreas transplantation and pancreatic islet transplantation. Whole organ transplantation has demonstrated benefits in prevention and reversal of diabetic complications with sustainable long-term outcomes. Pancreatic islet transplantation continues to be a field that needs further study to ascertain the true benefit of islet transplantation for diabetic complications. This can only be achieved with improvement in long-term islet allograft survival.

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