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. 2006 Feb;16(1):25-30.
doi: 10.1055/s-2005-922097.

Esthesioneuroblastoma: endonasal endoscopic treatment

Paolo G Castelnuovo  1 , Giovanni Delù, Federica Sberze, Andrea Pistochini, Cristhian Cambria, Paolo Battaglia, Maurizio Bignami
Affiliations

Esthesioneuroblastoma: endonasal endoscopic treatment

Paolo G Castelnuovo et al. Skull Base. 2006 Feb.

Abstract

Objectives: To illustrate endoscopic techniques used in the treatment of esthesioneuroblastoma and to advocate this method of management followed by radiation therapy in selected cases.

Methods: A retrospective case series of 10 patients with esthesioneuroblastomas treated between 1999 and 2004 at a tertiary referral center using endonasal techniques.

Results: Mean age of patients at presentation was 56.2 years (median 57 years). Seven patients were female and 3 patients were male. Kadish staging at presentation was: A - 3 patients, B - 5 patients, C - 2 patients. Dulguerov stage at presentation was: T1 - 4 patients, T2 - 4 patients, T3 - 2 patients. The period of follow-up ranged from 11 months to 74 months (mean 38.1 months, median 39 months). To date no recurrence has developed in any patient.

Conclusions: Our experience suggests that endoscopic surgery can be an effective method of management. Strict attention to selection criteria, careful surgical techniques, and regular follow-up are key elements for success.

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Figures

Figure 1
Figure 1
(A–C) Sagittal and coronal view of preoperative MRI showing tumor extension. (B–D) Sagittal and coronal view of postoperative MRI showing complete tumor excision.
See this image and copyright information in PMC

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