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. 1990 Jan;172(1):281-6.
doi: 10.1128/jb.172.1.281-286.1990.

Identification and sequence of the drpA gene from Escherichia coli

Z Zhou  1 , M Syvanen
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Identification and sequence of the drpA gene from Escherichia coli

Z Zhou et al. J Bacteriol. 1990 Jan.

Abstract

The drpA gene of Escherichia coli encodes a factor that is involved in global RNA synthesis. We establish that the drpA gene has been successfully cloned and describe the fine-structure map of three drpA-(Ts) mutations as well as the complete nucleotide sequence of the drpA gene. We identified a major sigma-70 promoter for the drpA gene on the bases of (i) its similarity to the consensus sequence and (ii) S1 protection and primer extension mapping data. In addition, the nucleotide sequence revealed a pair of dnaA boxes and a factor-independent terminator at the 5' end and 3' end of the gene, respectively. The deduced amino acid sequence of the DrpA protein showed a nucleotide-binding pocket found in some ATPases.

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References

    1. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5097-101 - PubMed
    1. Annu Rev Biochem. 1986;55:339-72 - PubMed
    1. J Bacteriol. 1988 Feb;170(2):889-94 - PubMed
    1. Cell. 1977 Nov;12(3):721-32 - PubMed
    1. Annu Rev Biochem. 1985;54:171-204 - PubMed

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