Kicking off adaptive immunity: the discovery of dendritic cells
- PMID: 16886239
- PMCID: PMC2118351
- DOI: 10.1084/jem.2037fta
Kicking off adaptive immunity: the discovery of dendritic cells
Abstract
In 1973, Ralph Steinman and Zanvil Cohn discovered an unusual looking population of cells with an unprecedented ability to activate naive T cells. Dubbed "dendritic cells," these cells are now known as the primary instigators of adaptive immunity.
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Comment on
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Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution.J Exp Med. 1973 May 1;137(5):1142-62. doi: 10.1084/jem.137.5.1142. J Exp Med. 1973. PMID: 4573839 Free PMC article.
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