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. 2006 Aug 8;67(3):494-6.
doi: 10.1212/01.wnl.0000227906.99570.cc.

Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: a case-control study

J H Bower  1 , D M Maraganore, B J Peterson, J E Ahlskog, W A Rocca
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Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: a case-control study

J H Bower et al. Neurology. .

Abstract

The authors studied the association of markers of inflammation with the later development of Parkinson disease (PD) using a case-control design (196 cases and 196 matched controls). The frequency of diseases of immediate-type hypersensitivity was significantly higher in cases than controls. In addition, cases used anti-inflammatory agents less frequently than controls (nonsignificant trend). The results may support the hypothesis that there is an inflammatory component in the pathogenesis of PD.

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