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. 2006 Aug;162(2):111-4.
doi: 10.1007/s11046-006-0039-4.

Efficacy of voriconazole in experimental Cryptococcus neoformans infection

Nikolaos Mavrogiorgos  1 , Oscar Zaragoza, Arturo Casadevall, Joshua D Nosanchuk
Affiliations

Efficacy of voriconazole in experimental Cryptococcus neoformans infection

Nikolaos Mavrogiorgos et al. Mycopathologia. 2006 Aug.

Abstract

Voriconazole is a third generation triazole with improved activity against many fungal pathogens. We examined the efficacy of voriconazole in a murine infection model and evaluated the drug's effect on cellular characteristics and serum polysaccharide levels. The antifungal reduced serum polysaccharide and significantly prolonged the survival of lethally infected animals.

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