doi: 10.1101/sqb.1974.039.01.115.
Studies on characterization of the integration sites of avian RNA tumor virus-specific DNA
- PMID: 169002
- DOI: 10.1101/sqb.1974.039.01.115
Item in Clipboard
Studies on characterization of the integration sites of avian RNA tumor virus-specific DNA
Cold Spring Harb Symp Quant Biol.
1975.
Abstract
A sequential hybridization procedure is described which allows the integration sites of viral-specific DNA to be characterized according to their reassociation kinetics. In addition, this approach enables us to estimate the size of the integrated viral DNA. Endogenous virus sequences in normal cells appear to be associated with cell sequences reiterated 1200 times, and each integration unit is approximately equal to one 35S RNA subunit. In AMV-infected cells, the additional AMV-specific DNA sequences reassociate as if they were integrated adjacent to unique cellular DNA or in tandem with the endogenous viral DNA sequences.
Similar articles
-
Evidence for tandem integration of avian myeloblastosis virus DNA with endogenous provirus in leukemic chicken cells.Proc Natl Acad Sci U S A. 1976 May;73(5):1749-53. doi: 10.1073/pnas.73.5.1749. Proc Natl Acad Sci U S A. 1976. PMID: 179099 Free PMC article.
-
Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous viral DNA in normal chicken cells.Proc Natl Acad Sci U S A. 1974 Aug;71(8):3152-6. doi: 10.1073/pnas.71.8.3152. Proc Natl Acad Sci U S A. 1974. PMID: 4369920 Free PMC article.
-
Quantitative and qualitative differences in DNA complementary to avian myeloblastosis virus between normal and leukemic chicken cells.Bibl Haematol. 1975;(40):525-36. doi: 10.1159/000397570. Bibl Haematol. 1975. PMID: 169823
-
Acquisition of viral DNA sequences in target organs of chickens infected with avian myeloblastosis virus.J Virol. 1975 Oct;16(4):783-9. doi: 10.1128/JVI.16.4.783-789.1975. J Virol. 1975. PMID: 170415 Free PMC article.
-
Ribonucleotide sequence homology among avian oncornaviruses.J Virol. 1975 Jan;17(1):106-113. doi: 10.1128/JVI.17.1.106-113.1976. J Virol. 1975. PMID: 173876 Free PMC article.
Cited by
-
Evidence for tandem integration of avian myeloblastosis virus DNA with endogenous provirus in leukemic chicken cells.Proc Natl Acad Sci U S A. 1976 May;73(5):1749-53. doi: 10.1073/pnas.73.5.1749. Proc Natl Acad Sci U S A. 1976. PMID: 179099 Free PMC article.
-
Variations in integration site of avian oncornaviruses in different hosts.J Virol. 1977 Feb;21(2):541-7. doi: 10.1128/JVI.21.2.541-547.1977. J Virol. 1977. PMID: 189085 Free PMC article.
-
Integration of proviral DNA in chicken cells infected with Schmidt-Ruppin Rous sarcoma virus is not enhanced by DNA repair.J Virol. 1977 Sep;23(3):533-42. doi: 10.1128/JVI.23.3.533-542.1977. J Virol. 1977. PMID: 197260 Free PMC article.
-
Distribution of bacteriophage phi 3T homologous deoxyribonucleic acid sequences in Bacillus subtilis 168, related bacteriophages, and other Bacillus species.J Bacteriol. 1981 Oct;148(1):91-100. doi: 10.1128/jb.148.1.91-100.1981. J Bacteriol. 1981. PMID: 6793558 Free PMC article.