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. 1990;91(1):111-2.
doi: 10.1159/000235099.

Basophil releasability in human hydatidosis

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Basophil releasability in human hydatidosis

A Aceti et al. Int Arch Allergy Appl Immunol. 1990.

Abstract

We studied immunoglobulin E (IgE)- and non-IgE-mediated releasability in basophils from 31 patients with hydatidosis. Histamine release to non-IgE-dependent stimuli did not differ significantly between normal individuals and patients with hydatidosis. On the contrary, an increased histamine liberation was obtained by challenging basophils from hydatid patients with anti-human IgE. It is concluded that Echinococcus granulosus infection induces an enhanced sensitivity of basophils to IgE-dependent stimuli.

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