Comment on

• Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412.

  Suntharalingam G, Perry MR, Ward S, Brett SJ, Castello-Cortes A, Brunner MD, Panoskaltsis N. Suntharalingam G, et al. N Engl J Med. 2006 Sep 7;355(10):1018-28. doi: 10.1056/NEJMoa063842. Epub 2006 Aug 14. N Engl J Med. 2006. PMID: 16908486 Clinical Trial.
• T-cell costimulation--biology, therapeutic potential, and challenges.

  Sharpe AH, Abbas AK. Sharpe AH, et al. N Engl J Med. 2006 Sep 7;355(10):973-5. doi: 10.1056/NEJMp068087. Epub 2006 Aug 14. N Engl J Med. 2006. PMID: 16908487 No abstract available.