Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2006 Aug;5(3):406-8.

Hepatic veno-occlusive disease induced by Gymura segetum: report of two cases

Hui-Fen Dai  1 , Yuan Gao, Ming Yang, Chao-Hui Yu, Zhu-Ying Gu, Wei-Xing Chen
Affiliations
  • PMID: 16911940
Case Reports

Hepatic veno-occlusive disease induced by Gymura segetum: report of two cases

Hui-Fen Dai et al. Hepatobiliary Pancreat Dis Int. 2006 Aug.

Abstract

Background: Hepatic veno-occlusive disease (VOD) or sinusoidal obstruction syndrome is associated with a high mortality because of its severity. Gymura segetum, a Chinese herbal medicine, is always used to cure injury and bleeding in rural areas in China. This study was undertaken to better understand VOD and its relations to the effect of Gymura segetum.

Methods: Between 2000 and 2002, two patients were admitted to our department because of VOD. Before admission, both of them had been injured and taken oral decoction of patent drug Gymura segetum. We analyzed the clinical manifestations, diagnosis and therapy of the two patients.

Results: Pyrrolizidine in Panax notginseng was proved to induce VOD. The diagnosis of VOD depended on hepatic biopsy.

Conclusion: Gymura segetum can induce VOD. More attention should be paid to its unsuscepted side effects.

PubMed Disclaimer

Publication types

Substances