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Review
. 2006 Sep;126(9):1931-2.
doi: 10.1038/sj.jid.5700457.

Non-pathogenic anti-desmoglein 3 IgG autoantibodies in Fogo Selvagem

Masayuki Amagai  1
Affiliations
Free article
Review

Non-pathogenic anti-desmoglein 3 IgG autoantibodies in Fogo Selvagem

Masayuki Amagai. J Invest Dermatol. 2006 Sep.
Free article

Abstract

The endemic form of pemphigus foliaceus, fogo selvagem, is caused by IgG autoantibodies directed against desmoglein 1 (Dsg1). Hilario-Vargas and his colleagues describe a high prevalence of IgG autoantibodies against Dsg3, the target antigen of pemphigus vulgaris, in a Brazilian population where fogo selvagem is endemic, although those patients do not develop any apparent clinical phenotype of pemphigus vulgaris.

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