Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1975 Aug 15;31(8):953-4.
doi: 10.1007/BF02358872.

Microsomal metabolism as a determinant of aflatoxin toxicity

T B Tilak, V Nagarajan, P G Tulpule
Review

Microsomal metabolism as a determinant of aflatoxin toxicity

T B Tilak et al. Experientia. .

Abstract

The evidences to incriminate the possible role of microsomal drug metabolizing system in aflatoxin toxicity in rat have been reviewed. It is suggested that an effective drug metabolism results in decreased acute toxicity and the products of metabolism are more carcinogenic than the native toxin to the rat liver.

PubMed Disclaimer

References

    1. J Natl Cancer Inst. 1973 Feb;50(2):439-48 - PubMed
    1. Proc Nutr Soc. 1967;26(1):12-7 - PubMed
    1. J Pathol. 1972 Jul;107(3):Pxv - PubMed
    1. Biochem Pharmacol. 1964 Jul;13:1037-51 - PubMed
    1. N Z Med J. 1968 Jan;67(426):Suppl:32-43 - PubMed