doi: 10.3109/01485019008986860.
Testicular macromolecular synthesis in men with varicocele
Affiliations
- PMID: 1691621
- DOI: 10.3109/01485019008986860
Item in Clipboard
Testicular macromolecular synthesis in men with varicocele
Arch Androl.
1990.
Abstract
The synthesis of DNA, RNA, and protein by varicocele testes with spermatogenic dysfunction was studied by examination of the levels of incorporation of [3H]thymidine, [14C]uridine, and [14C]leucine into the testicular tissue at 31 degrees C in vitro. The results suggest that DNA synthesis by the testis with moderate tubular damage is impaired whereas synthesis of RNA and protein is not. The cell regenerative ability of the testis with moderate tubular damage may be poor in spite of the preservation of testicular cell RNA and protein synthesis.
Similar articles
-
In vitro temperature sensitivity of DNA, RNA, and protein syntheses throughout puberty in human testis.Arch Androl. 1991 Jan-Feb;26(1):7-13. doi: 10.3109/01485019108987619. Arch Androl. 1991. PMID: 1706913
-
Obstruction of the tubuli recti and ductuli efferentes by dilated veins in the testes of men with varicocele and its possible role in causing atrophy of the seminiferous tubules.Int J Androl. 1984 Aug;7(4):309-23. doi: 10.1111/j.1365-2605.1984.tb00788.x. Int J Androl. 1984. PMID: 6439647
-
Depressed DNA synthesis in vitro by early prepubertal undescended human testis.Arch Androl. 1991 Jan-Feb;26(1):1-6. doi: 10.3109/01485019108987618. Arch Androl. 1991. PMID: 1706912
-
Normal and varicocele testis in adolescents.Asian J Androl. 2001 Dec;3(4):259-62. Asian J Androl. 2001. PMID: 11753469 Review.
-
[Tissue culture studies on compensatory testicular hypertrophy of the young rabbit after hemicastration].Hinyokika Kiyo. 1988 Apr;34(4):585-91. Hinyokika Kiyo. 1988. PMID: 2456677 Review. Japanese.