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. 1990 Apr 23;1034(1):114-7.
doi: 10.1016/0304-4165(90)90161-o.

Detergent extraction of the human alpha-beta interferon receptor: a soluble form capable of binding interferon

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Detergent extraction of the human alpha-beta interferon receptor: a soluble form capable of binding interferon

P Eid et al. Biochim Biophys Acta. .

Abstract

After examining a variety of detergents we find that receptors for human alpha interferon can be solubilized, in active form, from plasma membranes of lymphoid cells using the detergent CHAPS. The complexes formed, in solution, with interferon are stable enough to be separated chromatographically.

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