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Review
. 2007 Jan;89(1):1-20.
doi: 10.1016/j.biochi.2006.07.009. Epub 2006 Aug 4.

The control of histone lysine methylation in epigenetic regulation

Pamela Völkel  1 , Pierre-Olivier Angrand
Affiliations
Review

The control of histone lysine methylation in epigenetic regulation

Pamela Völkel et al. Biochimie. 2007 Jan.

Abstract

Histone lysine methylation plays a fundamental role in chromatin organization and function. This epigenetic mark is involved in many biological processes such as heterochromatin formation, chromosome X inactivation, genomic imprinting and transcriptional regulation. Here, we review recent advances in how histone lysine methylation participates in these biological events, and the enzymes that control histone lysine methylation and demethylation.

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