Review
doi: 10.1016/j.cub.2006.07.029.
Aging: progeria and the lamin connection
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- PMID: 16920618
- DOI: 10.1016/j.cub.2006.07.029
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Review
Aging: progeria and the lamin connection
Curr Biol.
.
Free article
Abstract
The relationship between progerias--diseases that resemble premature aging--and the normal aging process has been a source of debate in the aging research community. A recent study finds that LMNA, a gene targeted for mutation in Hutchinson Gilford Progeria Syndrome, may control the onset of aging-associated decline in normal fibroblasts.
Comment on
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Lamin A-dependent nuclear defects in human aging.Science. 2006 May 19;312(5776):1059-63. doi: 10.1126/science.1127168. Epub 2006 Apr 27. Science. 2006. PMID: 16645051 Free PMC article.
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