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Comment
. 2006 Aug 25;126(4):650-2.
doi: 10.1016/j.cell.2006.08.007.

When it comes to decisions, myeloid progenitors crave positive feedback

Dale Muzzey  1 , Alexander van Oudenaarden
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When it comes to decisions, myeloid progenitors crave positive feedback

Dale Muzzey et al. Cell. .
Free article

Abstract

Positive feedback is a ubiquitous feature of networks that establish and maintain cellular decisions. In this issue of Cell, Laslo et al. (2006) demonstrate how a feedback loop comprised of two mutual repressors regulates the differentiation of myeloid progenitors into either macrophages or neutrophils.

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