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. 1990 Jun;64(6):3126-9.
doi: 10.1128/JVI.64.6.3126-3129.1990.

Transcription of the baculovirus polyhedrin gene reduces the levels of an antisense transcript initiated downstream

B G Ooi  1 , L K Miller
Affiliations

Transcription of the baculovirus polyhedrin gene reduces the levels of an antisense transcript initiated downstream

B G Ooi et al. J Virol. 1990 Jun.

Abstract

A late 3.2-kilobase (kb) RNA initiated approximately 2 kb downstream of the 3' end of the Autographa californica nuclear polyhedrosis virus polyhedrin-coding sequence and traversed the polyhedrin gene in an antisense direction. This RNA was sense RNA for the two open reading frames flanking the polyhedrin gene. A mutant virus, vXpoly, which differs from wild-type virus only at the essential RNA initiation site in the polyhedrin promoter, exhibited higher levels of the 3.2-kb RNA than did wild-type virus during the polyhedrin transcriptional phase. Thus, transcription of the polyhedrin gene down regulates the levels of this 3.2-kb RNA.

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