Adverse effects of rapid isotonic saline infusion

Comment

M Eisenhut. Arch Dis Child. 2006 Sep.

. 2006 Sep;91(9):797.

doi: 10.1136/adc.2006.100123.

No abstract available

Conflict of interest statement

Competing interests: none declared

Is hyperchloraemic acidosis a problem in children with gastroenteritis rehydrated with normal saline? Authors' reply.
Neville K, Verge C, Rosenberg A, O'Meara M, Walker J. Neville K, et al. Arch Dis Child. 2007 May;92(5):466-7. doi: 10.1136/adc.2006.114876. Arch Dis Child. 2007. PMID: 17449531 Free PMC article. No abstract available.

Isotonic is better than hypotonic saline for intravenous rehydration of children with gastroenteritis: a prospective randomised study.
Neville KA, Verge CF, Rosenberg AR, O'Meara MW, Walker JL. Neville KA, et al. Arch Dis Child. 2006 Mar;91(3):226-32. doi: 10.1136/adc.2005.084103. Epub 2005 Dec 13. Arch Dis Child. 2006. PMID: 16352625 Free PMC article. Clinical Trial.

1. Neville K A, Verge C F, Rosenberg A R.et al Isotonic is better than hypotonic saline for intravenous rehydration of children with gastroenteritis: a prospective randomised study. Arch Dis Child 200691226–232. - PMC - PubMed
1. Prough D S, Bidani A. Hyperchloremic metabolic acidosis is a predictable consequence of intraoperative infusion of 0.9% saline. Anesthesiology 1999901247–1249. - PubMed
1. Wilkes N J, Woolf R, Mutch M.et al The effects of balanced versus saline‐based hetastarch and crystalloid solutions on acid‐base and electrolyte status and gastric mucosal perfusion in elderly surgical patients. Anesth Analg 200193811–816. - PubMed
1. Waters J H, Gottlieb A, Schoenwald P.et al Normal saline versus lactated Ringer's solution for intraoperative fluid management in patients undergoing abdominal aortic aneurysm repair: an outcome study. Anesth Analg 200193817–822. - PubMed
1. Bullivant E M A, Wilcox C S, Welch W J. Intrarenal vasoconstriction during hyperchloremia: role of thromboxane. Am J Physiol 1989256152–157. - PubMed