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. 1990 May 15;268(1):245-8.
doi: 10.1042/bj2680245.

A novel metalloproteinase originally isolated from brain myelin membranes is present in many tissues

A Chantry  1 , P Glynn
Affiliations

A novel metalloproteinase originally isolated from brain myelin membranes is present in many tissues

A Chantry et al. Biochem J. .

Abstract

A monoclonal antibody, CG4, was raised to a novel 60 kDa metalloproteinase purified from a bovine brain myelin glycoprotein fraction. Glycoproteins extracted from both myelin and nine different bovine tissues showed the 60 kDa CG4-immunoreactive band by immunoblotting in amounts that broadly paralleled enzymic activity of this metalloproteinase and varied relatively little among the tissues.

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