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Case Reports
. 2006 Sep;48(3):e27-9.
doi: 10.1053/j.ajkd.2006.05.018.

Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex

Ralf Wienecke  1 , Ingrid Fackler, Ulrich Linsenmaier, Karin Mayer, Thomas Licht, Matthias Kretzler
Affiliations
Case Reports

Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex

Ralf Wienecke et al. Am J Kidney Dis. 2006 Sep.

Abstract

A 19-year old patient with tuberous sclerosis presented with a renal angiomyolipoma. Because animal trials of tuberous sclerosis showed an effect of rapamycin on renal tumors, our patient was administered rapamycin for 6 months. During this time, the renal angiomyolipoma shrank significantly, regrew during an 8-month period, and decreased in size again after readministration of rapamycin.

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