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Case Reports
. 2006 Jan;2(1):54-8; quiz 58.
doi: 10.1038/ncpneuro0094.

Wernicke's encephalopathy: beyond alcoholism

Robin K Wilson  1 , Ralph W Kuncl, Andrea M Corse
Affiliations
Case Reports

Wernicke's encephalopathy: beyond alcoholism

Robin K Wilson et al. Nat Clin Pract Neurol. 2006 Jan.

Abstract

Background: A 17-year-old pregnant woman presented to hospital at 19 weeks' gestation with an 8-week history of hyperemesis gravidarum, 16.8 kg of weight loss, and new-onset weakness, dizziness and blurred vision. Examination of the patient showed confusion, papilledema, ophthalmoparesis, nystagmus, reduced hearing and truncal ataxia.

Investigations: Physical examination, abdominal ultrasound, fetal ultrasound, brain MRI, magnetic resonance angiography, magnetic resonance venography and cerebrospinal-fluid analysis.

Diagnosis: Wernicke's encephalopathy, hyperemesis gravidarum and fetal loss.

Management: Intravenous thiamine repletion and elimination of deficiency risk factors.

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