Review
Biology of the fibroblast growth factor gene family
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- PMID: 1693362
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Review
Biology of the fibroblast growth factor gene family
Isr J Med Sci.
1990 Apr.
Abstract
The biology of the fibroblast growth factor (FGF) gene family is reviewed. The structure, expression and known and putative functions of the seven members of this family characterized to date are discussed. These genes include: acidic and basic FGF, the INT.2 and HST proto-oncogenes and the recently characterized FGF.5, FGF.6 and KGF genes. These genes play a role in various processes such as cell proliferation, angiogenesis and embryogenesis, and possibly carcinogenesis.
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