Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006;10(4):159.
doi: 10.1186/cc5012.

Think outside the box: extrapulmonary manifestations of severe respiratory syncytial virus infection

Kentigern Thorburn  1 , C Anthony Hart
Affiliations
Review

Think outside the box: extrapulmonary manifestations of severe respiratory syncytial virus infection

Kentigern Thorburn et al. Crit Care. 2006.

Abstract

Extrapulmonary effects of severe respiratory syncytial virus (RSV) infection are not uncommon. Dr Eisenhut's systematic review of extrapulmonary manifestations of severe RSV infection clearly demonstrates clinical consequences peripheral to the lung parenchyma. The extrapulmonary impact of RSV infection raises questions as to whether these are direct RSV effects (i.e., RSV infection of site-specific tissue), secondary to parenchymal lung disease and its causative respiratory failure, or the result of inflammatory mediators dispersed from the provoked respiratory epithelium.

PubMed Disclaimer

Comment on

References

    1. Reynolds EOR, Cook CD. The treatment of bronchiolitis. J Pediatr. 1963;63:1205–1207. doi: 10.1016/S0022-3476(63)80215-2. - DOI - PubMed
    1. Eisenhut M. Extrapulmonary manifestations of severe respiratory syncytial virus infection – a systematic review. Crit Care. 2006;10:R107. doi: 10.1186/cc4984. - DOI - PMC - PubMed
    1. O'Donnell DR, McGarvey MJ, Tully JM, Balfour-Lynn IM, Openshaw PJ. Respiratory syncytial virus RNA in cells from the peripheral blood during acute infection. J Pediatr. 1998;133:272–274. doi: 10.1016/S0022-3476(98)70234-3. - DOI - PubMed
    1. Rohwedder A, Keminer O, Forster J, Schneider K, Schneider E, Werchau H. Detection of respiratory syncytial virus RNA in blood of neonates by polymerase chain reaction. J Med Virol. 1998;54:320–327. doi: 10.1002/(SICI)1096-9071(199804)54:4<320::AID-JMV13>3.0.CO;2-J. - DOI - PubMed
    1. Bowles NE, Ni J, Kearney DL, Pauschinger M, Schultheiss HP, McCarthy R, Hare J, Bricker JT, Bowles KR, Towbin JA. Detection of viruses in myocardial tissues by polymerase chain reaction. Evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol. 2003;42:466–472. doi: 10.1016/S0735-1097(03)00648-X. - DOI - PubMed

MeSH terms