Review
doi: 10.1016/j.bbamcr.2006.07.012.
Epub 2006 Jul 26.
Alpha-oxidation
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- PMID: 16934890
- DOI: 10.1016/j.bbamcr.2006.07.012
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Review
Alpha-oxidation
Biochim Biophys Acta.
2006 Dec.
Free article
Abstract
Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid) is a branched chain fatty acid, which is a constituent of the human diet. The presence of the 3-methyl group of phytanic acid prevents degradation by beta-oxidation. Instead, the terminal carboxyl group is first removed by alpha-oxidation. The mechanism of the alpha-oxidation pathway and the enzymes involved are described in this review.
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