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Review
. 2006 Sep-Oct;27(5):334-40.
doi: 10.1016/j.amjoto.2005.11.001.

Otosclerosis: etiopathogenesis and histopathology

Sebahattin Cureoglu  1 , Patricia A Schachern, Alfio Ferlito, Alessandra Rinaldo, Vladimir Tsuprun, Michael M Paparella
Affiliations
Review

Otosclerosis: etiopathogenesis and histopathology

Sebahattin Cureoglu et al. Am J Otolaryngol. 2006 Sep-Oct.

Abstract

Otosclerosis is a disease of the bony labyrinth manifesting clinically as a progressive conductive hearing loss, a mixed-type hearing loss, or a sensorineural hearing loss. The age of onset of the hearing loss caused by otosclerosis is principally between 15 and 40 years. Although histopathological inner ear changes due to otosclerosis have been very well documented, the true etiopathogenesis of the disease has yet to be described despite intensive research. Both genetic and environmental factors have been implicated, however.

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