Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Sep;19(3):323-34.
doi: 10.1016/j.ohc.2006.05.001.

Molecular biology of choroidal neovascularization

Ming Lu  1 , Anthony P Adamis
Affiliations
Review

Molecular biology of choroidal neovascularization

Ming Lu et al. Ophthalmol Clin North Am. 2006 Sep.

Abstract

VEGF plays a pivotal role in the neovascularization of the choroid in AMD. Anti-VEGF agents have been developed to target VEGF itself or its receptor signal transduction pathway, and have shown promising results in clinical trials. The combination of anti-VEGF strategies with established treatment modalities may have additional efficacy. Safe and effective drug-delivery systems are also required for the successful anti-VEGF therapies for AMD and other ocular diseases with CNV.

PubMed Disclaimer

MeSH terms

LinkOut - more resources