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Comment
. 2006 Aug 29;103(35):12957-8.
doi: 10.1073/pnas.0605627103. Epub 2006 Aug 22.

Unraveling the genetic basis of hybrid vigor

James A Birchler  1 , Hong Yao, Sivanandan Chudalayandi
Affiliations
Comment

Unraveling the genetic basis of hybrid vigor

James A Birchler et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

Conflict of interest statement: No conflicts declared.

Figures

Fig. 1.
Fig. 1.
Genetic models for heterosis. It is hypothesized in the diagrammed models that a phenotype or trait is controlled by multiple linked or unlinked loci (e.g., a, b, and c). (A) The dominance model. Inbred parents 1 and 2 carry slightly deleterious homozygous alleles (a and c in parent 1; b in parent 2). In the F1 hybrid, at each locus, the superior allele A, B, or C will complement the inferior alleles a, b, or c. This complementation could cause the F1 hybrid to exhibit a superior phenotype than the better of its parents. (B) The overdominance model. The homozygous alleles at the b locus are different between the inbred parent 1 (BB) and 2 (B′B′). When brought together in the F1 hybrid, allele B and B′ can interact to cause a superior phenotype compared with both the parental BB and B′B′ homozygous states. (C) The pseudooverdominance model. The superior phenotype in the F1 hybrid can be attributed to a small chromosomal region, which contains two or more different loci (e.g., a and b) that are linked in repulsion phase. The presence of superior alleles A and B in the hybrid leads to a better phenotype due to complementation, giving the impression of overdominance.
See this image and copyright information in PMC

Comment on

  • Overdominant quantitative trait loci for yield and fitness in tomato.
    Semel Y, Nissenbaum J, Menda N, Zinder M, Krieger U, Issman N, Pleban T, Lippman Z, Gur A, Zamir D. Semel Y, et al. Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):12981-6. doi: 10.1073/pnas.0604635103. Epub 2006 Aug 22. Proc Natl Acad Sci U S A. 2006. PMID: 16938842 Free PMC article.

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