Increase of the M phenotype among erythromycin-resistant Streptococcus pneumoniae isolates from Spain related to the serotype 14 variant of the Spain9V-3 clone
- PMID: 16940119
- PMCID: PMC1563508
- DOI: 10.1128/AAC.00269-06
Increase of the M phenotype among erythromycin-resistant Streptococcus pneumoniae isolates from Spain related to the serotype 14 variant of the Spain9V-3 clone
Abstract
Between 1998 and 2003 the rate of erythromycin resistance among pneumococci in Spain was 34.4%. Although the MLS(B) phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% (P < 0.01). Clonal dissemination of mef(E)-carrying strains of serotype 14 variant of the Spain(9V)-3 clone was the major contributor to this increase.
References
-
- Ardanuy, C., F. Tubau, J. Liñares, M. A. Domínguez, R. Pallarés, R. Martín, and The Spanish Pneumococcal Infection Study Network (G03/103). 2005. Distribution of subclasses mef(A) and mef(E) of the mef(A) gene among clinical isolates of macrolide-resistant (M-phenotype) Streptococcus pneumoniae, viridans group streptococci, and Streptococcus pyogenes. Antimicrob. Agents Chemother. 49:827-829. - PMC - PubMed
-
- Bryskier, A. 2002. Viridans group streptococci: a reservoir of resistant bacteria in oral cavities. Clin. Microbiol. Infect. 8:65-69. - PubMed
-
- Cochetti, I., M. Vecchi, M. Mingoia, E. Tili, M. R. Catania, A. Manzin, P. E. Valardo, and M. P. Montanari. 2005. Molecular characterization of pneumococci with efflux-mediated erythromycin resistance and identification of a novel mef gene subclass, mef(I). Antimicrob. Agents Chemother. 49:4999-5006. - PMC - PubMed
-
- Coffey, T. J., M. Daniels, M. C. Enright, and B. G. Spratt. 1999. Serotype 14 variants of the Spanish penicillin resistant serotype 9V clone of Streptococcus pneumoniae arose by large recombinational replacements of the cpsA-pbp1a region. Microbiology 145:2023-2031. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
