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. 2006 Sep;50(9):3189-91.
doi: 10.1128/AAC.00526-06.

In vitro activity of daptomycin against methicillin-resistant Staphylococcus aureus, including heterogeneously glycopeptide-resistant strains

Bram M W Diederen  1 , Inge van Duijn, Piet Willemse, Jan A J W Kluytmans
Affiliations

In vitro activity of daptomycin against methicillin-resistant Staphylococcus aureus, including heterogeneously glycopeptide-resistant strains

Bram M W Diederen et al. Antimicrob Agents Chemother. 2006 Sep.

Abstract

The purpose of the present study was to assess the in vitro activity of daptomycin against a well-defined collection of methicillin-resistant Staphylococcus aureus (MRSA) isolates (n = 98), including heterogeneously glycopeptide-resistant MRSA (hGISA) strains. Susceptibility testing was performed by using the Etest system. Daptomycin was potent against both glycopeptide-susceptible and hGISA strains.

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Figures

FIG. 1.
FIG. 1.
MICs for daptomycin for 79 glycopeptide-susceptible MRSA strains (A) and 19 heterogeneously glycopeptide-resistant MRSA strains (hGISA) (B) collected in The Netherlands as determined by using the Etest system. Gray bars, total number of isolates tested; black bars, percentage of the total tested.
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