Editorial
doi: 10.1038/ng0906-959.
Structural variants deconstruct the genome
- PMID: 16940994
- DOI: 10.1038/ng0906-959
Item in Clipboard
Editorial
Structural variants deconstruct the genome
Nat Genet.
2006 Sep.
Abstract
Common genomic structural variants predispose to deleterious de novo genomic rearrangements. Understanding how they do so will require population studies across the continuum of genomic variation and ethical discussion of the nature and uses of human variation.
Comment on
-
Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome.Nat Genet. 2006 Sep;38(9):1038-42. doi: 10.1038/ng1862. Epub 2006 Aug 13. Nat Genet. 2006. PMID: 16906162
-
Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability.Nat Genet. 2006 Sep;38(9):1032-7. doi: 10.1038/ng1858. Epub 2006 Aug 13. Nat Genet. 2006. PMID: 16906163
-
Genome structural variation and sporadic disease traits.Nat Genet. 2006 Sep;38(9):974-6. doi: 10.1038/ng0906-974. Nat Genet. 2006. PMID: 16941003 No abstract available.
Similar articles
-
Genome structural variation and sporadic disease traits.Nat Genet. 2006 Sep;38(9):974-6. doi: 10.1038/ng0906-974. Nat Genet. 2006. PMID: 16941003 No abstract available.
-
Structural variants: changing the landscape of chromosomes and design of disease studies.Hum Mol Genet. 2006 Apr 15;15 Spec No 1:R57-66. doi: 10.1093/hmg/ddl057. Hum Mol Genet. 2006. PMID: 16651370 Review.
-
[Structural variation in the human genome contributes to variation of traits].Tidsskr Nor Laegeforen. 2008 Sep 11;128(17):1951-5. Tidsskr Nor Laegeforen. 2008. PMID: 18787571 Review. Norwegian.
-
Structural variation in the human genome.N Engl J Med. 2007 Mar 15;356(11):1169-71. doi: 10.1056/NEJMcibr067658. N Engl J Med. 2007. PMID: 17360997 No abstract available.
-
Genomic rearrangements and sporadic disease.Nat Genet. 2007 Jul;39(7 Suppl):S43-7. doi: 10.1038/ng2084. Nat Genet. 2007. PMID: 17597781 Review.
Cited by
-
Complex chromosome 17p rearrangements associated with low-copy repeats in two patients with congenital anomalies.Hum Genet. 2007 Jul;121(6):697-709. doi: 10.1007/s00439-007-0359-6. Epub 2007 Apr 25. Hum Genet. 2007. PMID: 17457615 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
