Chromosome segregation: correcting improperly attached chromosomes
- PMID: 16950088
- DOI: 10.1016/j.cub.2006.08.008
Chromosome segregation: correcting improperly attached chromosomes
Abstract
Two new studies show that Aurora B kinase corrects improperly attached chromosomes by recruiting molecules necessary for eliminating the bad attachments and by regulating the turnover of the kinetochore fiber.
Comment on
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Aurora B is enriched at merotelic attachment sites, where it regulates MCAK.Curr Biol. 2006 Sep 5;16(17):1705-10. doi: 10.1016/j.cub.2006.07.057. Curr Biol. 2006. PMID: 16950107
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Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors.Curr Biol. 2006 Sep 5;16(17):1711-8. doi: 10.1016/j.cub.2006.07.022. Curr Biol. 2006. PMID: 16950108
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