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Review
. 2006 Oct;15(4):919-37, ix.
doi: 10.1016/j.chc.2006.05.013.

Puberty and depression

Affiliations
Review

Puberty and depression

Adrian Angold et al. Child Adolesc Psychiatr Clin N Am. 2006 Oct.

Abstract

Unipolar depression only becomes more common in girls than boys after the age of 13, as a result of an increased incidence of depressive episodes in girls at that time. This article reviews evidence that links multiple dimensions of maturation in the hypothalamo-pituitary-gonadal axis with this phenomenon. Effects of developmental status and timing have been implicated, but few studies have deployed either the measurement strategies or the statistical power needed to provide a satisfactory answer to the question regarding which components of puberty are most responsible.

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