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Case Reports
. 2006 Sep;44(9):3432-4.
doi: 10.1128/JCM.00856-06.

Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum

Mareva Giacchino  1 , Nadia Chiapello, Stefania Bezzio, Franca Fagioli, Paola Saracco, Alda Alfarano, Vincenza Martini, Giuseppe Cimino, Pietro Martino, Corrado Girmenia
Affiliations
Case Reports

Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum

Mareva Giacchino et al. J Clin Microbiol. 2006 Sep.

Abstract

We report three cases of invasive Geotrichum capitatum infection in patients with acute leukemia for which an enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Supernatants obtained from suspensions of 17 G. capitatum strains gave positive reactions with the Aspergillus galactomannan ELISA. These clinical and laboratory data seem to suggest that G. capitatum produces a soluble antigen that is cross-reactive with Aspergillus galactomannan.

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References

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