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Comparative Study
. 2006;52(7-8):363-6.

Novel intragenotype recombination in sapovirus

Tung Gia Phan  1 , Hainian Yan, Pattara Khamrin, Trinh Duy Quang, Shuvra Kanti Dey, Fumihiro Yagyu, Shoko Okitsu, Werner E G Müller, Hiroshi Ushijima
Affiliations
  • PMID: 16955634
Comparative Study

Novel intragenotype recombination in sapovirus

Tung Gia Phan et al. Clin Lab. 2006.

Abstract

Based on the genetic analysis, a novel, naturally occurring recombination between two distinct sapovirus subtypes (subtype a and subtype b) within genogroup I genotype 1 was identified. Breakpoint analysis of recombinant sapovirus showed that the recombination site was at the polymerase-capsid junction. This is the first report of the existence of acute gastroenteritis caused by intragenotype recombinant sapovirus. The results also provided evidence that the natural recombination occurs not only in sapovirus genogroup II but also in sapovirus genogroup I.

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