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Review
. 2006 Aug;35(1):71-82.
doi: 10.1016/j.transci.2006.05.008. Epub 2006 Sep 7.

Tissue distribution of blood group membrane proteins beyond red cells: evidence from cDNA libraries

Markus T Rojewski  1 , Hubert Schrezenmeier, Willy A Flegel
Affiliations
Review

Tissue distribution of blood group membrane proteins beyond red cells: evidence from cDNA libraries

Markus T Rojewski et al. Transfus Apher Sci. 2006 Aug.

Abstract

The proteins of blood group systems are expressed on red blood cells (RBC) by definition. We searched nucleotide databases of human expressed sequence tags (EST) to collate the distribution of 22 distinct membrane proteins in cells and tissues other than RBC. The documented blood group genes are: MNS, Rh, Lutheran, Kell, Duffy, Kidd, Diego, Yt, Xg, Scianna, Dombrock, Colton, Landsteiner-Wiener, Kx, Gerbich, Cromer, Knops, Indian, Ok, Raph, John-Milton-Hagen and Gill. The genes were grouped according to their overall and their relative expression in embryo and adults. We describe the distribution of EST in cells, tissues and cell lines with a focus on non-RBC tissues.

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