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. 2006 Nov;44(11):4211-3.
doi: 10.1128/JCM.01304-06. Epub 2006 Sep 6.

Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh

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Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh

G Balakrish Nair et al. J Clin Microbiol. 2006 Nov.

Abstract

We determined the types of cholera toxin (CT) produced by a collection of 185 Vibrio cholerae O1 strains isolated in Bangladesh over the past 45 years. All of the El Tor strains of V. cholerae O1 isolated since 2001 produced CT of the classical biotype, while those isolated before 2001 produced CT of the El Tor biotype.

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Figures

FIG. 1.
FIG. 1.
Amino acid sequence alignment of CT B subunits of representative El Tor V. cholerae isolates from Dhaka, Bangladesh, isolated between 2001 and 2005, that produced the classical subtype of CT, plotted relative to the El Tor reference (identical residues are indicated with dots). The amino acid sequences of the B subunits of V. cholerae 569B (classical) and N16961 (El Tor) were obtained from GenBank.

References

    1. Ansaruzzaman, M., N. A. Bhuiyan, G. B. Nair, D. A. Sack, M. Lucas, J. L. Deen, J. Ampuero, C. L. Chaignat, and the Mozambique Cholera Vaccine Demonstration Project Coordination Group. 2004. Cholera in Mozambique, variant of Vibrio cholerae. Emerg. Infect. Dis. 10:2057-2059. - PMC - PubMed
    1. Clemens, J. D., D. A. Sack, J. R. Harris, F. van Loon, J. Chakraborty, F. Ahmed, M. R. Rao, M. R. Khan, M. Yunus, N. Huda, B. F. Stanton, B. A. Kay, R. Eeckels, J. D. Clemens, M. R. Rao, B. A. Kay, D. A. Sack, J. R. Harris, B. F. Stanton, S. Walter, R. Eeckels, A.-M. Svennerholm, and J. Holmgren. 1990. Field trial of oral cholera vaccines in Bangladesh: results from a three-year follow-up. Lancet 335:270-273. - PubMed
    1. Dziejman, M., E. Balon, D. Boyd, C. M. Fraser, J. F. Heidelberg, and J. J. Mekalanos. 2002. Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease. Proc. Natl. Acad. Sci. USA 99:1556-1561. - PMC - PubMed
    1. Finkelstein, R. A., F. Burks, A. Zupan, W. S. Dallas, C. O. Jacob, and D. S. Ludwig. 1987. Epitopes of the cholera family of enterotoxins. Rev. Infect. Dis. 9:544-561. - PubMed
    1. Finkelstein, R. A. 25 February 2006, posting date. Cholera, Vibrio cholerae O1 and O139, and other pathogenic vibrios. [Online.] http://gsbs.utmb.edu/microbook/ch024.htm. - PubMed

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