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Case Reports
. 2005 Jun;26(3):115-7.
doi: 10.1007/s10792-006-9002-0. Epub 2006 Sep 7.

Unusual macular lesions in a patient with neurofibromatosis type-1

Eibhlín M McLoone  1 , Trevor A S Buchanan
Affiliations
Case Reports

Unusual macular lesions in a patient with neurofibromatosis type-1

Eibhlín M McLoone et al. Int Ophthalmol. 2005 Jun.

Abstract

Background: Retinal involvement in neurofibromatosis type-1 (NF-1) is rare.

Methods: We present a case report of a 49-year-old man with neurofibromatosis who developed bilateral macular lesions associated with gradual reduction of visual acuity.

Results: Electrophysiology revealed an absent pattern electroretinogram. Fluorescein angiography demonstrated mottled hyperfluorescence of the maculae in the early-phase fluorescein angiogram followed by late staining of the lesions.

Conclusions: Our patient had unusual bilateral macular lesions which had some features suggestive of adult-onset foveomacular vitelliform dystrophy. To the best of our knowledge, there have been no previous reports of such macular lesions occurring in association with NF-1.

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