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Review
. 2007 Jan;275(1):1-3.
doi: 10.1007/s00404-006-0234-z. Epub 2006 Sep 7.

Single-day therapy: an expert opinion on a recent development for the episodic treatment of recurrent genital herpes

Stephen Tyring  1 , Gary Richwald, Kamal Hamed
Affiliations
Review

Single-day therapy: an expert opinion on a recent development for the episodic treatment of recurrent genital herpes

Stephen Tyring et al. Arch Gynecol Obstet. 2007 Jan.

Abstract

One common method for treating recurrent genital herpes outbreaks is 3-5 day episodic therapy with nucleoside analogues. However, since maximum viral replication occurs within 24 h after the onset of symptoms, short-term patient-initiated episodic therapy started at prodromal onset or at the first appearance of lesions in patients without a prodrome may represent an important option. In a recent randomized trial, single-day famciclovir treatment decreased lesion healing time and the duration of pain and other symptoms by approximately 2 days compared to placebo, and prevented progression to a full outbreak in almost one in four patients. Because single-day treatment is more convenient than traditional therapies, it may lead to improved patient compliance and better overall management of recurrent genital herpes outbreaks.

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References

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