Comment
doi: 10.1016/j.cell.2006.08.023.
Targeting protein stability with a small molecule
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- PMID: 16959558
- DOI: 10.1016/j.cell.2006.08.023
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Comment
Targeting protein stability with a small molecule
Cell.
.
Free article
Abstract
Both genetic approaches and small-molecule inhibitors can be used to perturb protein function. Banaszynski et al. (2006) now describe a strategy to regulate the stability of a target protein, in which specificity is provided by a genetically encoded tag and temporal control is imparted by a small molecule.
Comment on
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A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules.Cell. 2006 Sep 8;126(5):995-1004. doi: 10.1016/j.cell.2006.07.025. Cell. 2006. PMID: 16959577 Free PMC article.
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