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. 2006 Oct;12(10):1030-3.
doi: 10.1111/j.1469-0691.2006.01523.x.

Treatment of bone and joint infections caused by Gram-negative bacilli with a cefepime-fluoroquinolone combination

L Legout  1 , E Senneville, R Stern, Y Yazdanpanah, C Savage, M Roussel-Delvalez, B Rosele, H Migaud, Y Mouton
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Free article

Treatment of bone and joint infections caused by Gram-negative bacilli with a cefepime-fluoroquinolone combination

L Legout et al. Clin Microbiol Infect. 2006 Oct.
Free article

Abstract

A 3-year retrospective study evaluated the effectiveness and safety of cefepime plus a fluoroquinolone for treating bone and joint infections caused by Gram-negative bacilli (GNB) in 28 patients. Intra-operative cultures yielded primarily Pseudomonas spp. and Enterobacter cloacae. Full recovery (cure) was observed in 79% of patients. There were no serious adverse effects and no resistant organisms were isolated. The results of the study confirmed the safety and effectiveness of cefepime combined with a fluoroquinolone for the treatment of bone and joint infections caused by Gram-negative bacilli.

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