Hepatobiliary surgery: lessons learned from live donor hepatectomy

Abstract

The liver is unique in the rapid tissue regeneration occurs after resection or injury, and affords the surgeon the opportunity to safely remove up to 60% to 70% of the liver volume for treatment of cancer or for use as a live donor graft for transplantation. The complex development of the liver and biliary system in utero results in multiple and complicated anatomic variations. The hepatobiliary surgeon of today must be able to integrate a broadening array of radiologic and liver resection techniques that may improve patient safety and surgical outcome. Equally important is the ability to quickly recognize postoperative complications so that prompt intervention can be instituted. Successful outcome requires a balance between sound judgement, technical acumen, and attention to detail. Herein, we provide lessons learned from live donor liver transplantation that are directly applicable to any patient undergoing major hepatic resection.