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Review
. 2007 Jan;12(1):1-10.
doi: 10.1007/s00775-006-0165-y. Epub 2006 Sep 9.

Proton thrusters: overview of the structural and functional features of soluble tetrahaem cytochromes c3

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Review

Proton thrusters: overview of the structural and functional features of soluble tetrahaem cytochromes c3

Ricardo O Louro. J Biol Inorg Chem. 2007 Jan.

Abstract

Tetrahaem cytochromes c (3) from sulfate-reducing bacteria have revealed exquisite complexity in their ligand binding properties and they couple the cooperative binding of two electrons with the binding of protons. In this review, the molecular mechanisms for these cooperative effects are described, and the functional consequences of these cooperativities are discussed in the context of the general mechanisms of biological energy transduction and the specific physiological metabolism of Desulfovibrio.

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