Folate: a magic bullet or a double edged sword for colorectal cancer prevention?
- PMID: 16966698
- PMCID: PMC1856406
- DOI: 10.1136/gut.2006.095463
Folate: a magic bullet or a double edged sword for colorectal cancer prevention?
Abstract
Low folate status might inhibit colorectal carcinogenesis and high folate status may promote colorectal carcinogenesis, contradicting findings from epidemiological studies showing an inverse relationship between folate status and risk of colorectal cancer
Conflict of interest statement
Conflict of interest: None declared.
Comment on
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Low folate levels may protect against colorectal cancer.Gut. 2006 Oct;55(10):1461-6. doi: 10.1136/gut.2005.085480. Epub 2006 Apr 25. Gut. 2006. PMID: 16638790 Free PMC article.
References
-
- Kim Y I. Role of folate in colon cancer development and progression. J Nutr 20031333731–9S. - PubMed
-
- Campbell N R. How safe are folic acid supplements? Arch Intern Med 19961561638–1644. - PubMed
-
- Kim Y I. Will mandatory folic acid fortification prevent or promote cancer? Am J Clin Nutr 2004801123–1128. - PubMed
-
- Kim Y I. Folate and carcinogenesis: Evidence, mechanisms, and implications. J Nutr Biochem 19991066–88. - PubMed
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