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. 2006 Aug;10(3):483-9.
doi: 10.1007/s11030-006-9045-1. Epub 2006 Sep 12.

An easy access to 2-Amino-5,6-dihydro-3H-pyrimidin-4-one building blocks: the reaction under conventional and microwave conditions

Konstantin S Ostras  1 , Nikolay Yu Gorobets, Sergey M Desenko, Vladimir I Musatov
Affiliations

An easy access to 2-Amino-5,6-dihydro-3H-pyrimidin-4-one building blocks: the reaction under conventional and microwave conditions

Konstantin S Ostras et al. Mol Divers. 2006 Aug.

Abstract

A new one-stage fast multicomponent synthesis of title compounds leads to products in 21-55% isolated yields under both conventional and microwave conditions. The primary amino group in the building blocks can be easily acylated by various usual electophilic agents that can be utilized in the synthesis of diverse heterocylic compounds libraries.

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References

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