Randomized Controlled Trial
doi: 10.1016/s0885-3924(06)80004-7.
A randomized double-blind crossover trial of intravenous lidocaine in the treatment of neuropathic cancer pain
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- PMID: 16967580
- DOI: 10.1016/s0885-3924(06)80004-7
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Randomized Controlled Trial
A randomized double-blind crossover trial of intravenous lidocaine in the treatment of neuropathic cancer pain
J Pain Symptom Manage.
1992 Apr.
Free article
Abstract
In a randomized, double-blind, crossover study, we evaluated the effect of intravenous lidocaine (5 mg/kg body weight over 30 min) on the neuropathic pain of advanced cancer patients. Pain intensity, assessed by a visual analogue scale, did not show any significant difference between lidocaine and placebo infusion. The blinded choice of patients and investigators also suggested no significant improvement from lidocaine when given by this regimen. Intravenous lidocaine does not appear to have a significant analgesic effect on neuropathic cancer pain.
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