Comment
doi: 10.1016/j.immuni.2006.08.011.
Tolling for autoimmunity-prime time for 7
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- PMID: 16979573
- DOI: 10.1016/j.immuni.2006.08.011
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Comment
Tolling for autoimmunity-prime time for 7
Immunity.
2006 Sep.
Free article
Abstract
The reason certain self-antigens are consistently targeted by autoantibodies may be because they are self-adjuvants. Two papers in this issue of Immunity provide important insights into the contribution of Toll-like receptors in systemic autoimmune disease (Berland et al., 2006; Christensen et al., 2006).
Comment on
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Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice.Immunity. 2006 Sep;25(3):429-40. doi: 10.1016/j.immuni.2006.07.014. Immunity. 2006. PMID: 16973388
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Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.Immunity. 2006 Sep;25(3):417-28. doi: 10.1016/j.immuni.2006.07.013. Immunity. 2006. PMID: 16973389
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